Document Detail

Emergency aortic valve replacement in systemic lupus erythematosus.
MedLine Citation:
PMID:  16815755     Owner:  NLM     Status:  MEDLINE    
The valvular heart disease in systemic lupus erythematosus (SLE) is associated with substantial morbidity and mortality. Current therapy includes symptomatic measures and valve replacement. Overall mortality of valve replacement has been reported to be as high as 25%. Most cases of Libman-Sacks endocarditis in the literature reported dominant aortic regurgitation. We present this unusual case of a young female patient with SLE and glomerulonephritis warranting emergency isolated aortic valve replacement (AVR) for severe calcific aortic stenosis. The literature is reviewed with specific focus on the pathogenesis of and acute treatment options for this extremely rare occurrence.
Sanjay Kumar; Bharati Sinha; Edwin Ravikumar
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-07-11
Journal Detail:
Title:  Heart, lung & circulation     Volume:  15     ISSN:  1443-9506     ISO Abbreviation:  Heart Lung Circ     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-12-04     Completed Date:  2007-03-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100963739     Medline TA:  Heart Lung Circ     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  397-9     Citation Subset:  IM    
Department of Cardiothoracic Surgery, 177, 'D' Floor, Yorkshire Heart Centre, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
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MeSH Terms
Aortic Valve / pathology,  transplantation*
Aortic Valve Stenosis / etiology,  pathology,  surgery*
Emergency Treatment
Heart Valve Prosthesis Implantation*
Lupus Erythematosus, Systemic / complications*

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