Document Detail

Emergency Department Pneumonia Patients Who do not Meet the Six-Hour Criteria for Antibiotic Administration: Do They Have a Different Clinical Presentation?
MedLine Citation:
PMID:  23024737     Owner:  NLM     Status:  PubMed-not-MEDLINE    
BACKGROUND: The Joint Commission (JC) has set a quality of care standard for emergency department (ED) patients diagnosed with community acquired pneumonia (CAP) that states that they are to receive antibiotics within six hours of presentation to the ED. Hospitals have been able to demonstrate that the majority of patients meet these criteria, yet there are still many who do not. Previously published studies have reported that there are several issues that contribute to prolonged times to antibiotic administration including ED crowding and atypical clinical presentations. This study was undertaken to identify factors existing early in the patient encounter that may be associated with failure to meet the Joint Commission's six-hour standard for antibiotic administration.
METHODS: This was an IRB-approved, retrospective observational study covering 36 months in an academic emergency department. All adults with an admission diagnosis of CAP were eligible but were excluded if their discharge diagnosis was not CAP, if hospitalized within the previous 14 days, or if HIV positive. Univariate analysis and multiple logistic regression with stepwise variable selection were performed comparing patients who met and did not meet JC standards. The analysis included demographics (age, sex), chief complaint at triage and to doctor (fever, dyspnea, cough, chest pain, weakness/fatigue, abdominal pain), presence of altered mental status, triage vital signs, co-morbidities, day of week and time of day of presentation.
RESULTS: A total of 736 cases were eligible; 199 cases met exclusion criteria; 43 charts were unavailable; 494 were included in the study group (363 with complete antibiotic time records; 131 were incomplete). From the univariate analysis, respiratory rate (RR) and oxygen saturation were the only factors that met Bonferroni criteria for statistical significance when comparing those who met and did not meet the JC six-hour criteria (RR 25 ± 9 vs 22 ± 6 breaths/minute, respectively, P = 0.002; oxygen saturation 87 ± 10% vs 92 ± 5%, respectively, P < 0.001). Multiple logistic regression identified triage pulse rate, oxygen saturation, presence of altered mental status, hour of day, and day of week as variables associated with time to antibiotic administration. Chances for meeting the standard were increased by 10% for each 5-beat increase in pulse rate or 1% decrease in oxygen saturation. If the person exhibited altered mental status, they were > 3.5 times more likely to meet the 6-hour criteria. If they presented to ED between 3 PM and 10 PM chances of meeting criteria were reduced by about 65%. If they presented on a Thursday, chances improved 2.8 times.
CONCLUSIONS: Compared to patients who did meet Joint Commission criteria, those who did not receive antibiotics within 6 hours were likely to have triage pulse rates and O(2) saturation levels closer to normal, thus contributing to diagnostic uncertainty. They were also likely to present to the ED at the most crowded time of day. Likelihood to meet JC criteria was improved if O(2) saturation was below normal, pulse rate was elevated, if they exhibited mental confusion, or if they presented to the ED very early or very late in the day, or on a lower census day.
Susan H Watts; E David Bryan
Related Documents :
4034777 - Conservative and operative treatment of mallet finger.
16002487 - A 7-year follow-up of patellar tendon and hamstring tendon grafts for arthroscopic ante...
18039357 - Mechanical properties during healing of achilles tendon ruptures to predict final outco...
6392457 - Primary flexor tendon repair in "no man's land".
22784487 - Outcome after isolated polyethylene tibial insert exchange in revision total knee arthr...
18976257 - Efficacy of alpha lipoic acid in burning mouth syndrome: a randomized, placebo-treatmen...
Publication Detail:
Type:  Journal Article     Date:  2012-09-12
Journal Detail:
Title:  Journal of clinical medicine research     Volume:  4     ISSN:  1918-3011     ISO Abbreviation:  J Clin Med Res     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-01     Completed Date:  2012-10-02     Revised Date:  2013-05-30    
Medline Journal Info:
Nlm Unique ID:  101538301     Medline TA:  J Clin Med Res     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  338-45     Citation Subset:  -    
Texas Tech University Health Sciences Center, Paul L Foster School of Medicine, Department of Emergency Medicine, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Assessment of sleep-related breathing disorders in patients with duchenne muscular dystrophy.
Next Document:  Intraoperative adrenal insufficiency in a patient with prader-willi syndrome.