Document Detail


Emergency department bedside ultrasonographic measurement of the caval index for noninvasive determination of low central venous pressure.
MedLine Citation:
PMID:  19556029     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STUDY OBJECTIVE: Among adult emergency department (ED) patients undergoing central venous catheterization, we determine whether a greater than or equal to 50% decrease in inferior vena cava diameter is associated with a central venous pressure of less than 8 mm Hg. METHODS: Adult patients undergoing central venous catheterization were enrolled in a prospective, observational study. Inferior vena cava inspiratory and expiratory diameters were measured by 2-dimensional bedside ultrasonography. The caval index was calculated as the relative decrease in inferior vena cava diameter during 1 respiratory cycle. The correlation of central venous pressure and caval index was calculated. The sensitivity, specificity, and positive and negative predictive values of a caval index greater than or equal to 50% that was associated with a central venous pressure less than 8 mm Hg were estimated. RESULTS: Of 73 patients, the median age was 63 years and 60% were women. Mean time and fluid administered from ultrasonographic measurement to central venous pressure determination were 6.5 minutes and 45 mL, respectively. Of the 73 participants, 32% had a central venous pressure less than 8 mm Hg. The correlation between caval index and central venous pressure was -0.74 (95% confidence interval [CI] -0.82 to -0.63). The sensitivity of caval index greater than or equal to 50% to predict a central venous pressure less than 8 mm Hg was 91% (95% CI 71% to 99%), the specificity was 94% (95% CI 84% to 99%), the positive predictive value was 87% (95% CI 66% to 97%), and the negative predictive value was 96% (95% CI 86% to 99%). CONCLUSION: Bedside ultrasonographic measurement of caval index greater than or equal to 50% is strongly associated with a low central venous pressure. Bedside measurements of caval index could be a useful noninvasive tool to determine central venous pressure during the initial evaluation of the ED patient.
Authors:
Arun D Nagdev; Roland C Merchant; Alfredo Tirado-Gonzalez; Craig A Sisson; Michael C Murphy
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Publication Detail:
Type:  Journal Article     Date:  2009-06-25
Journal Detail:
Title:  Annals of emergency medicine     Volume:  55     ISSN:  1097-6760     ISO Abbreviation:  Ann Emerg Med     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-22     Completed Date:  2010-03-15     Revised Date:  2010-09-07    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  290-5     Citation Subset:  AIM; IM    
Copyright Information:
Copyright (c) 2009 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.
Affiliation:
Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, RI 02903, USA.
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MeSH Terms
Descriptor/Qualifier:
Aged
Central Venous Pressure* / physiology
Emergency Service, Hospital*
Female
Humans
Hypotension / ultrasonography*
Male
Middle Aged
Point-of-Care Systems*
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity
Vena Cava, Inferior / physiopathology,  ultrasonography*
Comments/Corrections
Comment In:
Rev Clin Esp. 2010 Sep;210(8):411

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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