Document Detail


Emergence in france of multiple clones of clinical Streptococcus pneumoniae isolates with high-level resistance to amoxicillin.
MedLine Citation:
PMID:  10348775     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The genetic relatedness of French isolates of Streptococcus pneumoniae highly resistant to amoxicillin (MIC, >/=4 microg/ml, equal to or exceeding those of penicillin) was investigated by molecular fingerprinting. The results suggest that high-level resistance to amoxicillin has emerged within preexisting penicillin-resistant clones.
Authors:
C Doit; C Loukil; F Fitoussi; P Geslin; E Bingen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Antimicrobial agents and chemotherapy     Volume:  43     ISSN:  0066-4804     ISO Abbreviation:  Antimicrob. Agents Chemother.     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-06-23     Completed Date:  1999-06-23     Revised Date:  2013-04-17    
Medline Journal Info:
Nlm Unique ID:  0315061     Medline TA:  Antimicrob Agents Chemother     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1480-3     Citation Subset:  IM    
Affiliation:
Laboratoire de Microbiologie, Hôpital Robert Debré, 75019 Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Amoxicillin / pharmacology*
DNA Fingerprinting
Humans
Microbial Sensitivity Tests
Penicillin Resistance*
Penicillins / pharmacology*
Polymorphism, Restriction Fragment Length
Serotyping
Streptococcus pneumoniae / classification,  drug effects*,  genetics
Chemical
Reg. No./Substance:
0/Penicillins; 26787-78-0/Amoxicillin
Comments/Corrections

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