| Emergence of VIM-1-carbapenemase-producing Enterobacter cloacae in Tyrol, Austria. | |
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MedLine Citation:
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PMID: 22194339 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The rapid emergence and dissemination of carbapenemase producing Enterobacter sp. and other Enterobacteriaceae poses a considerable threat to the care of hospitalized patients and to public health. In this study, Enterobacter isolates demonstrating decreased susceptibility to carbapenems detected at the Division of Hygiene and Medical Microbiology, Innsbruck Medical University, between January 2006 and December 2010 were tested for blaVIM-1, blaNDM-1, blaIMP, blaKPC and blaOXA-48 using a multiplex PCR with published primers. Pulsed field gel electrophoresis (PFGE) was performed to determine the genetic relatedness. In total, 33 isolates (28 Enterobacter cloacae and 5 Enterobacter aerogenes) were collected during the study period. From 2006 to 2009, between 2 and 7 isolates were found per year. In 2010, a significant increase of carbapenem resistant strains was observed (n = 12). In all 28 isolates of Enterbacter cloacae, the blaVIM-1 gene was detected. Typing of Enterobacter cloacae by PFGE revealed three distinct clusters of which the biggest contained 18 isolates. These findings demonstrate the emergence of VIM-1-producing Enterobacter in Tyrol, Western Austria. The clonal relationship confirms the risk of spread of these organisms and their possible persistence over time. |
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Authors:
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Ingrid Heller; Katharina Grif; Dorothea Orth |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-22 |
Journal Detail:
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Title: Journal of medical microbiology Volume: - ISSN: 1473-5644 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0224131 Medline TA: J Med Microbiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Division of Hygiene and Medical Microbiology, Innsbruck Medical University. |
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