| Emergence of cytomegalovirus disease in patients receiving temozolomide: report of two cases and literature review. | |
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MedLine Citation:
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PMID: 20455691 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Temozolomide chemotherapy has become part of the therapy used to treat glioblastoma multiforme and refractory anaplastic astrocytoma. Temozolomide frequently produces profound lymphopenia. We report 2 cases of cytomegalovirus disease that occurred in patients receiving temozolomide therapy and review 4 additional cases reported in the literature. Narrow monitoring with cytomegalovirus antigenemia assay should be considered for recommendation. |
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Authors:
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Yolanda Meije; Manuel Lizasoain; Ana García-Reyne; Pilar Martínez; Virginia Rodríguez; Francisco López-Medrano; Rafael San Juan; Antonio Lalueza; José María Aguado |
Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Volume: 50 ISSN: 1537-6591 ISO Abbreviation: Clin. Infect. Dis. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-20 Completed Date: 2010-07-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9203213 Medline TA: Clin Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: e73-6 Citation Subset: IM |
Affiliation:
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Infectious Diseases Unit, Hospital Universitario 12 de Octubre, Madrid, Spain. yolandameije@gmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antineoplastic Agents, Alkylating / adverse effects, therapeutic use* Central Nervous System Neoplasms / complications, drug therapy Cytomegalovirus Infections / complications*, epidemiology Dacarbazine / adverse effects, analogs & derivatives*, therapeutic use Female Glioblastoma / complications, drug therapy Humans Lymphoma, B-Cell / complications, drug therapy Male Middle Aged Opportunistic Infections / complications |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents, Alkylating; 4342-03-4/Dacarbazine; 85622-93-1/temozolomide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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