| Embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa in men with obstructive azoospermia. | |
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MedLine Citation:
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PMID: 16952508 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine whether the injection of testicular spermatozoa results in more viable embryos (higher implantation rate) than injection of epididymal spermatozoa in cases of obstructive azoospermia. DESIGN: Retrospective analysis of 265 cases of testicular sperm aspiration (TESA) and percutaneous sperm aspiration (PESA), including 185 cases of obstructive azoospermia. SETTING: Private Infertility clinic. PATIENT(S): None, charts review. INTERVENTION(S): None, charts review. MAIN OUTCOME MEASURE(S): Clinical pregnancy rate (PR), implantation rate. RESULT(S): Although fertilization rates were higher in the PESA group, implantation rates were significantly better in the TESA group. There was also a trend to higher ongoing PR and lower miscarriage rates in TESA cases. CONCLUSION(S): In cases of obstructive azoospermia, embryos generated using testicular spermatozoa have higher developmental potential than those obtained using epididymal spermatozoa. |
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Authors:
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Dmitri Dozortsev; Rosa Neme; Michael P Diamond; Soraya Abdelmassih; Vicente Abdelmassih; Flavio Oliveira; Roger Abdelmassih |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 86 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2006 Sep |
Date Detail:
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Created Date: 2006-09-05 Completed Date: 2006-09-25 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 606-11 Citation Subset: IM |
Affiliation:
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Clínica e Centro de Pesquisa em Reprodução Humana Roger Abdelmassih, São Paulo, Brazil. dmitri@dozortsev.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brazil
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epidemiology Embryo, Mammalian / pathology* Epididymis / pathology* Female Humans Infertility, Male / epidemiology, therapy Male Oligospermia / epidemiology, therapy* Pregnancy Pregnancy Rate* Retrospective Studies Sperm Injections, Intracytoplasmic / methods, statistics & numerical data Spermatozoa / pathology*, transplantation* Testis / pathology* Treatment Outcome United States / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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