Document Detail

Embryonic stem-cell culture as a tool for developmental cell biology.
MedLine Citation:
PMID:  17522593     Owner:  NLM     Status:  MEDLINE    
The cell biology of the early processes of mammalian embryogenesis, such as germ-layer formation, has been technically challenging to study owing to the size and accessibility of mammalian embryos. Embryonic stem cells, which can generate the three germ layers in vitro, are useful for studying embryogenesis at the cellular level. So, how can the study of embryonic stem cells and their differentiation provide a deeper understanding of the cell biology of early development?
Shin-Ichi Nishikawa; Lars Martin Jakt; Takumi Era
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nature reviews. Molecular cell biology     Volume:  8     ISSN:  1471-0072     ISO Abbreviation:  Nat. Rev. Mol. Cell Biol.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-24     Completed Date:  2007-07-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100962782     Medline TA:  Nat Rev Mol Cell Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  502-7     Citation Subset:  IM    
Laboratory of Stem Cell Research, Center for Developmental Biology, Minatojima Minamimachi 2-2-3, Chuoku, Kobe, 650-0047 Japan.
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MeSH Terms
Cell Culture Techniques*
Cell Differentiation / physiology
Cell Lineage
Cells, Cultured
Developmental Biology
Embryonic Stem Cells / cytology,  physiology*

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