Document Detail

Embryonic development of the ventral body wall and its congenital malformations.
MedLine Citation:
PMID:  9138714     Owner:  NLM     Status:  MEDLINE    
Congenital abdominal wall defects, frequently associated with other anomalies, are found in many forms. Consequently, there is still controversy in the literature concerning nomenclature, classification, and pathogenesis. Recently, we proposed a new nomenclature and classification of abdominal wall defects based on the early development of the umbilical cord and of the ventral body wall. According to this classification the complete spectrum of abdominal wall defects, including cloacal exstrophy, bladder exstrophy, and epispadias, can be subdivided into four types: primary (thoraco-)abdominoschisis, omphalocele, body wall dysplasia, and secondary (thoraco-)abdominoschisis. Each type is characterized by its specific configuration of the placenta, the membranes, the umbilical cord, and the fetus. Anomalies such as urachal remnants and omphalomesenteric duct malformations can be explained by disturbances during later stages of umbilical cord development.
C Vermeij-Keers; N G Hartwig; J F van der Werff
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Seminars in pediatric surgery     Volume:  5     ISSN:  1055-8586     ISO Abbreviation:  Semin. Pediatr. Surg.     Publication Date:  1996 May 
Date Detail:
Created Date:  1997-05-06     Completed Date:  1997-05-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9216162     Medline TA:  Semin Pediatr Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  82-9     Citation Subset:  IM    
Department of Anatomy, Erasmus University/University Hospital, Rotterdam, The Netherlands.
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MeSH Terms
Abdominal Muscles / abnormalities*,  embryology*
Bladder Exstrophy / embryology
Cloaca / abnormalities,  embryology
Embryonic and Fetal Development
Epispadias / embryology
Hernia, Umbilical / embryology
Prune Belly Syndrome / embryology
Terminology as Topic

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