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Embryonal rhabdomyosarcoma of the paranasal sinuses: a case report and review of literature.
MedLine Citation:
PMID:  25232439     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Embryonal rhabdomyosarcoma (ERMS) is a rare malignancy with a poor outcome. In this article, we describe a case of ERMS in the paranasal sinuses from a 60-year-old male patient. ERMS derived from the paranasal sinuses is extremely rare. The diagnosis of ERMS must be based on histological findings and immunohistochemical findings. In this case, microscopic observation showed tumor cells were arranged in flocked sheets, cord-like and acinar-like by hyperplastic fibrous tissue. And ERMS tissues were immunopositive for myogenin, desmin, MSA, CD56, vimentin, CD99, Syn and Ki-67 (40%+), and immunonegative for CK, EMA, LCA, GFAP, NSE, S-100, HMB-45 and Melan-A. Here, the patient was treated with multimodal therapy including endoscopic surgery, chemotherapy and radiation, but the patient's postoperative recovery is not too smooth.
Authors:
Pei-Xue Wu; Yan-Fang Liang; Jin-Cheng Zeng; Jian-Bo Ruan; Dong-Ping Kang; Can Chen; Tao Zeng; Qiu-Liang Wu; Wei-Hua Xu
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Publication Detail:
Type:  Journal Article     Date:  2014-08-15
Journal Detail:
Title:  International journal of clinical and experimental medicine     Volume:  7     ISSN:  1940-5901     ISO Abbreviation:  Int J Clin Exp Med     Publication Date:  2014  
Date Detail:
Created Date:  2014-09-18     Completed Date:  2014-09-18     Revised Date:  2014-09-20    
Medline Journal Info:
Nlm Unique ID:  101471010     Medline TA:  Int J Clin Exp Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2369-72     Citation Subset:  -    
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