| Embryonal (Botryoides) Rhabdomyosarcoma of the Uterus Harboring a Primitive Neuroectodermal Tumor Component. | |
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MedLine Citation:
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PMID: 22653355 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The association of a uterine sarcoma botryoides of the adolescence with a primitive neuroectodermal tumor is reported in a 12-year-old patient who presented with abnormal vaginal bleeding that occurred after passing per vaginam a polypoid mass. The sarcoma botryoides of the adolescence exhibited foci of cartilage and a central area of primitive neuroectodermal tumor with a trabecular, adamantiform histology and prominent angiogenesis. Primitive neuroectodermal tumor was positive for vimentin, synaptophysin, neuron-specific enolase, CD99, and SOX2 and negative for both the FLI-1 fusion protein and the rearrangement of ESWR1 gene. The neoplasm exhibited a nonaggressive behavior similar to sarcoma botryoides of the adolescence, being alive and well 3 y after its presentation. This is possibly related to its polypoid nature and the absence of invasive features at its uterine insertion level. A conservative approach without further resection and chemotherapy was indicated taking into account the patient's age. |
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Authors:
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Simona Stolnicu; Pablo Goyenaga; Monica Hincu; Cristina Marian; Raquel Murillo; Francisco F Nogales |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-30 |
Journal Detail:
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Title: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists Volume: - ISSN: 1538-7151 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-6-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8214845 Medline TA: Int J Gynecol Pathol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Pathology, University of Medicine of Pharmacy (S.S., C.M.), Targu Mures Obstetrics and Gynecology Hospital (M.H.), Brasov, Romania San Cecilio University Hospital (P.G., F.F.N.), Granada Hospital el Mar (R.M.), Barcelona, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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