| Embryology and epidemiology of cleft lip and palate. | |
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MedLine Citation:
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PMID: 17366840 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Craniofacial anomalies, in particular cleft lip and palate, are major human birth defects with a worldwide frequency of 1 in 700 and substantial clinical impact. This article reviews the embryology of the face, lip, and palate to enhance the understanding of the pathogenesis of these lesions, with particular attention to the period of susceptibility during gestation, complexity, and the factors that may influence their development. It includes an overview of the prevalence and environmental and genetic causes of cleft lip-with or without cleft palate- and cleft palate. |
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Authors:
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N Bernheim; M Georges; C Malevez; A De Mey; A Mansbach |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: B-ENT Volume: 2 Suppl 4 ISSN: 1781-782X ISO Abbreviation: B-ENT Publication Date: 2006 |
Date Detail:
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Created Date: 2007-03-19 Completed Date: 2007-04-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101247842 Medline TA: B-ENT Country: Belgium |
Other Details:
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Languages: eng Pagination: 11-9 Citation Subset: IM |
Affiliation:
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Department of Otorhinolaryngology, Head and Neck Surgery, The Cleft Lip and Palate Team, Hôpital Universitaire des Enfants Reine Fabiola, Brussels, Belgium. nathalie.bernheim@huderf.be |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cleft Lip
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embryology*,
epidemiology,
genetics Cleft Palate / embryology*, epidemiology, genetics Disease Susceptibility Embryonic Development Face / embryology Humans Lip / embryology Palate / embryology Prevalence Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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