Document Detail

Embryological fusion between the ducts of the ventral and dorsal primordia of the pancreas occurs in two manners.
MedLine Citation:
PMID:  9163788     Owner:  NLM     Status:  MEDLINE    
The junction between the main pancreatic duct and the accessory duct has been thought to be the site of fusion between the ducts of the ventral and the dorsal primordia of the pancreas. The aim of this study was to investigate the fusion point between the ventral and the dorsal pancreatic ducts and to determine whether there is any relationship between the configuration of the pancreatic ducts and the manner of embryological fusion. Pancreatography was performed at 22 consecutive autopsies. Immunohistochemical staining of pancreatic polypeptide (PP) was performed because PP cells were rich in the ventral pancreas but poor in the dorsal pancreas. We identified two types of fusion. In one type, the ventral and the dorsal pancreatic ducts fuse at their junction (one-point fusion). In the other type, the two ducts fuse not only at the proximal site but at a second, more distal site (two-point fusion). Analysis of the pancreatograms showed that the distance between the junction and the major papilla in two-point fusion is significantly shorter than in one-point fusion (p < 0.01). These results indicate a close correlation between the pattern seen on pancreatograms and the manner of embryological fusion.
H Tadokoro; T Kozu; F Toki; M Kobayashi; N Hayashi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pancreas     Volume:  14     ISSN:  0885-3177     ISO Abbreviation:  Pancreas     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-07-18     Completed Date:  1997-07-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8608542     Medline TA:  Pancreas     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  407-14     Citation Subset:  IM    
Department of Internal Medicine, Tokyo Women's Medical College, Japan.
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MeSH Terms
Membrane Fusion / physiology*
Middle Aged
Pancreas / anatomy & histology,  embryology*,  metabolism
Pancreatic Ducts / embryology,  metabolism,  radiography

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