Document Detail

Embryological background of truncular venous malformation in the extracranial venous pathways as the cause of chronic cerebro spinal venous insufficiency.
MedLine Citation:
PMID:  20351665     Owner:  NLM     Status:  MEDLINE    
The truncular venous malformation (VM) represents an embryologically defective vein where developmental arrest has occurred during the vascular trunk formation period in the 'later stage' of the embryonic development. A relatively simple truncular VM lesion such as a venous web at the hepatic venous outlet causes portal hypertension giving a profound damage/impact to the liver. A similar condition involving the head and neck venous system may cause chronic cerebro-spinal venous insufficiency (CCSVI) and may be involved in the development or exacerbation of multiple sclerosis.
A B Lee; J Laredo; R Neville
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International angiology : a journal of the International Union of Angiology     Volume:  29     ISSN:  1827-1839     ISO Abbreviation:  Int Angiol     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-30     Completed Date:  2010-07-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402693     Medline TA:  Int Angiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  95-108     Citation Subset:  IM    
Department of Vascular Surgery, Georgetown University Hospital, Washington, DC, USA.
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MeSH Terms
Azygos Vein / abnormalities*,  physiopathology
Chronic Disease
Collateral Circulation
Constriction, Pathologic
Jugular Veins / abnormalities*,  physiopathology
Multiple Sclerosis / etiology,  pathology,  physiopathology
Regional Blood Flow
Spinal Cord / blood supply*
Vascular Malformations / complications*,  pathology,  physiopathology
Venae Cavae / abnormalities*,  physiopathology
Venous Insufficiency / etiology*,  pathology,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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