Document Detail


Embryo score is a better predictor of pregnancy than the number of transferred embryos or female age.
MedLine Citation:
PMID:  11239536     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To compare the value of 17 IVF variables, including a new mean score of transferred embryos (MSTE), in predicting pregnancy rate. DESIGN: Retrospective study. SETTING: Private IVF unit. PATIENT(S): Women who underwent 10,000 embryo transfers. MAIN OUTCOME MEASURE(S): Duration of infertility, type of infertility, female age, rank of IVF attempt, type of ovarian treatment, progesterone level, sperm count, sperm motility, sperm morphology, number of retrieved oocytes, number of mature oocytes, maturation rate, number of embryos obtained, fertilization rate, number of transferred embryos, cumulative embryo score (CES), mean score of transferred embryos (MSTE), and pregnancy rate. RESULT(S): Outcome of IVF-ET was significantly correlated with female age, type of infertility, number of retrieved oocytes, number of mature oocytes, maturation rate, embryos obtained, fertilization rate, transferred embryos, CES, and MSTE. Multivariate analysis demonstrated that MSTE was a better predictor of pregnancy than the number of transferred embryos and female age. CONCLUSION(S): Embryo quality is the best predictor of pregnancy. The embryo score described herein should be used in IVF-ET programs to choose the best embryos for transfer.
Authors:
P Terriou; C Sapin; C Giorgetti; E Hans; J L Spach; R Roulier
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  75     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-03-12     Completed Date:  2001-04-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  525-31     Citation Subset:  IM    
Affiliation:
Institut de Médecine de la Reproduction, Marseille, France. philippe.terriou@wanadoo.fr
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors*
Cell Count
Embryo Transfer*
Embryo, Mammalian / physiology*
Female
Fertilization in Vitro
Humans
Infertility / therapy
Male
Multivariate Analysis
Oocytes / physiology
Pregnancy
Progesterone / blood
Retrospective Studies
Sperm Count
Sperm Motility
Spermatozoa / abnormalities
Chemical
Reg. No./Substance:
57-83-0/Progesterone
Comments/Corrections
Comment In:
Fertil Steril. 2001 Dec;76(6):1286-8   [PMID:  11730774 ]
Fertil Steril. 2002 Sep;78(3):650; author reply 650-1   [PMID:  12215354 ]

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