Document Detail

Embryo reduction of multifetal pregnancies following assisted reproduction treatment: a modification of the transvaginal ultrasound-guided technique.
MedLine Citation:
PMID:  11006205     Owner:  NLM     Status:  MEDLINE    
First-trimester transvaginal embryo reduction is an effective alternative for the management of multifetal pregnancy in assisted reproduction. We have modified the transvaginal technique by performing an intracardiac embryo puncture until asystolia is verified, without the injection of any substances. Any aspiration of embryo tissues or amniotic fluid was avoided. A total of 149 multifetal pregnancies was reduced to twins (n = 134) or singletons (n = 15) at early gestational age (7.8 +/- 0.8 weeks). Eleven cases (7.3%) of miscarriage, two cases (1.3%) of chorioamnionitis, and 17 cases (11.4%) of transient spotting were recorded as postoperative complications. Vanishing of one embryo occurred in four cases (3.0%) of those reduced to twins. The baby take-home rate was 89.5% for twins and 80.0% for singletons. Pregnancy outcome was analysed and compared with a control group of women with non-reduced multiple pregnancies. The birth weight of singleton pregnancies after reduction was lower (2929 +/- 160 versus 3291 +/- 422 g; P < 0.02). These studies show that early transvaginal intracardiac embryo puncture is an effective and safe technique.
G Ibérico; J Navarro; L Blasco; C Simón; A Pellicer; J Remohí
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  15     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2000-12-13     Completed Date:  2000-12-13     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2228-33     Citation Subset:  IM    
Instituto Valenciano de Infertilidad (IVI), Valencia, Spain.
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MeSH Terms
Chorioamnionitis / etiology
Infant, Newborn
Obstetric Labor, Premature
Postoperative Complications
Pregnancy Outcome
Pregnancy Reduction, Multifetal / methods*
Reproductive Techniques
Ultrasonography, Interventional / methods*
Ultrasonography, Prenatal / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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