Document Detail


Embryo development and gestation using fresh and vitrified oocytes.
MedLine Citation:
PMID:  20185514     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The objective of this study was to compare the gestational results obtained with vitrified/thawed oocytes by a novel vitrification method (Vitri-ingá) to results obtained with fresh oocytes. METHODS: A total of 125 IVF-ET procedures carried out over 2008 were analysed, in which 79 patients received embryos from fresh oocytes (Group 1), and 46 patients received embryos from vitrified/thawed oocytes using Vitri-ingá (Group 2). Fresh and vitrified/thawed oocytes were fertilized and embryos were transferred. Fertilization, pregnancy and implantation rates were compared. RESULTS: Vitrified oocytes presented a survival rate of 84.9%. Fertilization, pregnancy and implantation rates showed no statistically significant differences between fresh and cryopreserved/thawed groups (81.3, 51.9, 21.3% and 80.8, 45.6 and 14.9%, respectively). Only the average number of blastomeres in Group 1 (6.86 +/- 2.07) was significantly higher than in Group 2 (6.35 +/- 2.26; P = 0.010). CONCLUSIONS: Despite some differences in the patient groups, the clinical results of this study demonstrated that the Vitri-ingá method preserves the potential of human vitrified oocytes for fertilization and further development.
Authors:
Carlos Gilberto Almodin; Vania Cibele Minguetti-Camara; Cassia Lopes Paixao; Priscila Cardoso Pereira
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article     Date:  2010-02-25
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  25     ISSN:  1460-2350     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-14     Completed Date:  2010-07-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  England    
Other Details:
Languages:  eng     Pagination:  1192-8     Citation Subset:  IM    
Affiliation:
Materbaby Human Reproduction-Human Reproduction, Av XV de Novembro, 1232, Maringá, Paraná 87013230, Brazil. almodin@materbaby.com.br
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MeSH Terms
Descriptor/Qualifier:
Adult
Blastomeres / cytology
Cell Survival
Cryopreservation / instrumentation,  methods*
Embryo Implantation
Embryo Transfer
Embryonic Development*
Female
Fertilization in Vitro
Humans
Oocytes / cytology*
Pregnancy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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