Document Detail

Embolotherapy of large pulmonary arteriovenous malformations: long-term results.
MedLine Citation:
PMID:  9354504     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The purpose of this study was to document the long-term results of transcatheter embolotherapy of large pulmonary arteriovenous malformations (PAVMs). METHODS: From a data base of 221 consecutive patients with PAVMs treated by embolotherapy between 1978 and 1995, 45 patients with 52 PAVMs, supplied by feeding arteries 8 mm in diameter or larger, were selected for a retrospective investigation. RESULTS: Of 45 patients with 52 large PAVMs, 38 patients (84%) with 44 PAVMs (85%) were cured by the first embolotherapy (mean follow-up, 4.7 years). Acute periprocedural complications included self-limited pleurisy (31%), angina secondary to air embolus (2%), and paradoxical embolization of a device during deployment (4%). None of these events led to short- or long-term sequelae. Seven patients (16%) had persistence of the PAVM attributable to either recanalization (n = 4) or interim accessory artery growth (n = 3). Two of these patients presented with ischemic stroke several years after the initial treatment. Persistent PAVMs (n = 8) were retreated successfully by a second procedure (n = 7), or a third procedure (n = 1) (mean follow-up, 5.9 and 5.3 years, respectively). CONCLUSIONS: Embolotherapy of large PAVMs results in permanent occlusion in an overwhelming majority of patients. Continued patency due to recanalization or accessory artery growth is easily detected and treated.
D W Lee; R I White; T K Egglin; J S Pollak; P B Fayad; J A Wirth; M M Rosenblatt; K W Dickey; C M Burdge
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  64     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1997 Oct 
Date Detail:
Created Date:  1997-11-13     Completed Date:  1997-11-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  930-9; discussion 939-40     Citation Subset:  AIM; IM    
Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, Connecticut, USA.
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MeSH Terms
Arteriovenous Malformations / therapy*
Embolization, Therapeutic*
Follow-Up Studies
Middle Aged
Outcome Assessment (Health Care)*
Pulmonary Artery / abnormalities*
Pulmonary Veins / abnormalities*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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