| Embolization of Meningiomas: Comparison of Safety between Calibrated Microspheres and Polyvinyl-Alcohol Particles as Embolic Agents. | |
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MedLine Citation:
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PMID: 23079408 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE:During embolization of meningiomas, intratumoral hemorrhagic complications may occur, especially with the use of small particle sizes. We compared the rate of hemorrhagic complications in 55 patients embolized with 400-μm calibrated microspheres (Embozene) with a historical cohort of 198 patients embolized with smaller PVA particles.MATERIALS AND METHODS:Between September 2009 and February 2012, fifty-five patients with 55 meningiomas were embolized with 400-μm calibrated microspheres. Indications for embolization were preoperative in 47 and before radiosurgery in 2 patients; and in 6 patients, embolization was offered as sole therapy. There were 35 women and 20 men with a mean age of 60.3 years. Mean meningioma diameter was 53 mm (range, 23-97 mm). Hemorrhagic complications were recorded.RESULTS:There were no hemorrhagic complications in the 55 embolized patients (0%; 95% CI, 0.0%-7.8%). The difference in complication rates between 400-μm calibrated microspheres in this study (0 of 55, 0%) and small PVA particles (45-150 μm) in the historical cohort (9 of 108, 8.3%) was just short of significance (P = .066). The difference in complication rates between 400-μm calibrated microspheres (0 of 55, 0%) and larger PVA particles (150-250 μm) in the historical cohort (1 of 93, 1.1%) was not significant (P = .8).CONCLUSIONS:In this series, embolization of meningiomas by using large (400-μm) calibrated microspheres did not result in any hemorrhagic complications. |
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Authors:
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M Sluzewski; W J van Rooij; P N Lohle; G N Beute; J P Peluso |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-18 |
Journal Detail:
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Title: AJNR. American journal of neuroradiology Volume: - ISSN: 1936-959X ISO Abbreviation: AJNR Am J Neuroradiol Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003708 Medline TA: AJNR Am J Neuroradiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Departments of Radiology and Neurosurgery, St. Elisabeth Ziekenhuis, Tilburg, the Netherlands. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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