Document Detail

Embolic materials for endovascular treatment of cerebral lesions.
MedLine Citation:
PMID:  9195334     Owner:  NLM     Status:  MEDLINE    
Recently developed soft microcatheters can be maneuvered endovascularly into the brain, permitting treatment of lesions without conventional neurosurgery. Progress in biomaterial science has contributed significantly to the development of this new therapeutic modality termed intravascular neurosurgery or interventional neuroradiology. Although embolic materials play an important role, ideal materials have yet to be devised. Various embolic materials in clinical use are reviewed, such as cyanoacrylates, ethylene-vinyl alcohol copolymer mixtures, Ethibloc, ethanol, estrogen, poly(vinyl acetate), cellulose acetate polymer, poly(vinyl alcohol), gelatin sponges, microfibrillar collagen, surgical silk sutures, detachable balloons, and coils. The materials are reviewed in the context of treatment application for various brain lesions, such as arteriovenous malformations, cerebral aneurysms, and head and neck tumors. Further developments in biomaterial polymer science can bring about progress against brain diseases.
Y Matsumaru; A Hyodo; T Nose; T Hirano; S Ohashi
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of biomaterials science. Polymer edition     Volume:  8     ISSN:  0920-5063     ISO Abbreviation:  J Biomater Sci Polym Ed     Publication Date:  1997  
Date Detail:
Created Date:  1997-08-13     Completed Date:  1997-08-13     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  9007393     Medline TA:  J Biomater Sci Polym Ed     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  555-69     Citation Subset:  IM    
Department of Neurosurgery, University of Tsukuba, Ibaraki, Japan.
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MeSH Terms
Catheterization, Peripheral / instrumentation*
Cerebrovascular Disorders / therapy*
Embolization, Therapeutic / instrumentation*
Head and Neck Neoplasms / blood supply,  therapy
Intracranial Aneurysm / therapy
Intracranial Arteriovenous Malformations / therapy
Materials Testing*

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