| Elysiapyrones from Elysia diomedea. Do such metabolites evidence an enzymatically assisted electrocyclization cascade for the biosynthesis of their bicyclo[4.2.0]octane core? | |
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MedLine Citation:
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PMID: 15673253 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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[structure: see text] Biogenetically interesting polypropionate-derived metabolites 1 and 2, featuring an unprecedented skeleton, have been isolated from the sea slug Elysia diomedea. Their enantiomeric character indicates that the current spontaneous electrocyclization cascade biogenetic hypothesis for the bicyclo[4.2.0]octane core must be enzymatically aided. These compounds are isomeric with the 15-nor-9,10-deoxytridachione/15-norphotodeoxytridachione pair of metabolites and encourage speculation about their biosynthetic relationship. |
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Authors:
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Mercedes Cueto; Luis D'Croz; Juan L Maté; Aurelio San-Martín; José Darias |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Organic letters Volume: 7 ISSN: 1523-7060 ISO Abbreviation: Org. Lett. Publication Date: 2005 Feb |
Date Detail:
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Created Date: 2005-01-27 Completed Date: 2006-05-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100890393 Medline TA: Org Lett Country: United States |
Other Details:
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Languages: eng Pagination: 415-8 Citation Subset: IM |
Affiliation:
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Instituto de Productos Naturales y Agrobiología del CSIC, Avda. Astrofísico F. Sánchez 3, 38206 La Laguna, Tenerife, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bicyclo Compounds, Heterocyclic / chemistry* Cyclization Electrochemistry Hydroxyl Radical Magnetic Resonance Spectroscopy Molecular Conformation Mollusca / chemistry* Stereoisomerism |
| Chemical | |
Reg. No./Substance:
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0/Bicyclo Compounds, Heterocyclic; 0/elysiapyrone A; 0/elysiapyrone B; 3352-57-6/Hydroxyl Radical |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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