Document Detail


Elusive equilibrium: the challenge of interpreting receptor pharmacology using calcium assays.
MedLine Citation:
PMID:  20977466     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
LINKED ARTICLES: This article is part of a themed section on Analytical Receptor Pharmacology in Drug Discovery. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2010.161.issue-6.
Authors:
Steven J Charlton; Georges Vauquelin
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  British journal of pharmacology     Volume:  161     ISSN:  1476-5381     ISO Abbreviation:  Br. J. Pharmacol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-27     Completed Date:  2011-09-30     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  7502536     Medline TA:  Br J Pharmacol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1250-65     Citation Subset:  IM    
Copyright Information:
© 2010 The Authors. British Journal of Pharmacology © 2010 The British Pharmacological Society.
Affiliation:
Novartis Institutes for Biomedical Research, Horsham, UK. steven.charlton@novartis.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Calcium / metabolism*
Calcium Signaling / physiology
Humans
Kinetics
Pharmacology / methods
Protein Binding / physiology
Radioligand Assay / methods*
Receptors, Drug / metabolism*
Receptors, G-Protein-Coupled / metabolism*
Signal Transduction / physiology
Chemical
Reg. No./Substance:
0/Receptors, Drug; 0/Receptors, G-Protein-Coupled; 7440-70-2/Calcium
Comments/Corrections

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