Document Detail

Elucidating nonlinear baroreflex and respiratory contributions to heart rate variability in obstructive sleep apnea syndrome.
MedLine Citation:
PMID:  17281219     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Using a Volterra-Wiener model and the Laguerre expansion technique, we estimated in a previous study the parameters that characterize linear and the second order effects of respiration ("RSA") and arterial blood pressure ("ABR") on heart rate. RSA and ABR gains were significantly lower in Obstructive Sleep Apnea (OSA) patients than in normal subjects. During sleep, ABR gain increased in normals but remained unchanged in OSA. In the present work, we investigated the physiological interpretation of the nonlinear components of the described model of heart rate variability, by means of simulation on the computed linear and nonlinear kernels. Our results indicate that the 2<sup>nd</sup>order kernels reflect specific characteristics of the RSA and ABR mechanisms, such as a RSA frequency response dependence upon tidal volume, saturation in the ABR-Blood Pressure relation, and respiratory modulation of ABR.
J Jo; M K Khoo; A Blasi; A Baydur; R Juarez
Related Documents :
9483299 - A comparison of underwater bubble continuous positive airway pressure with ventilator-d...
12554839 - A longitudinal observation of early pulmonary responses to cotton dust.
12531119 - Systemic hypertension and obstructive sleep apnoea.
6391309 - Nasal airway positive pressure in patients with occlusive sleep apnea. methods and feas...
19426239 - A new supraglottic airway device: lma-supreme, comparison with lma-proseal.
3823749 - Nasal vasomotor responses in man to breath holding and hyperventilation recorded by mea...
8293769 - Coronary vasodilation to acetylcholine, adenosine and bradykinin in dogs: effects of in...
3721749 - Flow cessation pressures in the rabbit tenuissimus muscle.
15126919 - Cardiovascular hypertrophy in one-kidney, one-clip renal hypertension is resistant to h...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  4     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2005  
Date Detail:
Created Date:  2007-02-06     Completed Date:  2012-10-02     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4430-3     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Time-Varying Analysis of the Heart Rate Variability during Arousals from Sleep.
Next Document:  Improving prediction of protein subcellular localization using evolutionary information and sequence...