Document Detail


Elimination of sulfamethazine residues from swine.
MedLine Citation:
PMID:  500475     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Tissue concentrations of sulfamethazine in swine fed the drug at the rate of 500 g/ton of ration (550 g/1,000 kg) for a 30-day period depleted to 0.1 ppm or less within 4 to 10 days after withdrawal of medicated feed. Depletion from the tissues and plasma of treated pigs showed a linear relationship with time when the concentrations were plotted on a semilogarithmic graph. Six untreated pigs that were placed on bedding in pens formerly occupied by the treated group developed tissue residues at or above 0.1 ppm sulfamethazine; the mean plasma concentration of sulfamethazine reached 2.8 ppm by day 15.
Authors:
G Samuelson; D M Whipple; D H Showalter; W C Jacobson; G E Heath
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  175     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  1979 Sep 
Date Detail:
Created Date:  1980-01-28     Completed Date:  1980-01-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  449-52     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / metabolism
Animals
Kidney / metabolism
Liver / metabolism
Muscles / metabolism
Sulfamethazine / blood,  metabolism*
Swine / metabolism*
Chemical
Reg. No./Substance:
57-68-1/Sulfamethazine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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