Document Detail

Elimination of false-positive cytomegalovirus immunoglobulin M-fluorescent-antibody reactions with immunoglobulin M serum fractions.
MedLine Citation:
PMID:  197118     Owner:  NLM     Status:  MEDLINE    
The cytomegalovirus fluorescent-antibody test for immunoglobline M (IgM) antibody was found positive in seven of nine infants with congenital rubella infection, in addition to eight of eight infants with confirmed cytomegalovirus infection. When the test was repeated on IgM fractions of the same sera freed from IgG by ultracentrifugation, only negative reactions were observed in those from the rubella-infected infants, whereas IgM fractions from the cytomegalovirus-infected infants remained positive.
P W Robertson; V Kertesz; M J Cloonan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  6     ISSN:  0095-1137     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1977-10-20     Completed Date:  1977-10-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  174-5     Citation Subset:  IM    
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MeSH Terms
Antibodies, Viral / analysis*
Cytomegalovirus / immunology*
Cytomegalovirus Infections / immunology*
False Positive Reactions
Fluorescent Antibody Technique
Immunoglobulin G
Immunoglobulin M / analysis*
Rubella / immunology
Reg. No./Substance:
0/Antibodies, Viral; 0/Immunoglobulin G; 0/Immunoglobulin M

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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