Document Detail

Eligibility for biventricular pacing in patients with an implantable cardioverter defibrillator.
MedLine Citation:
PMID:  12798829     Owner:  NLM     Status:  MEDLINE    
Implantable cardioverter defibrillator (ICD)-therapy prevents sudden death in patients at high risk, but incidence of death due to heart failure remains unaltered. Recent data suggest that biventricular (BV) pacing is useful in patients with heart failure. It is unclear, how many patients with an ICD indication may have an indication for BV pacing. Therefore all patients who received an ICD were analyzed for eligibility of BV pacing using the following criteria: NYHA class III or IV, QRS duration >120 ms, depressed LVEF. Three hundred and ninety consecutive patients received an ICD from June 1996 to March 2001. Underlying disease was ischemic heart disease in 66%. In the 390 patients the mean LVEF was 36+/-17%, 20% were in NYHA class III-IV and 16% were in NYHA class II with an LVEF <30%. Of these 140 patients, 79 had a QRS duration >120 ms. Thus, 79 (20%) patients were eligible for BV pacing in addition to ICD-therapy. Patients who received a BV pacemaker in addition to ICD-therapy had a superior survival, improved in NYHA class and showed a significantly lower hospitalization rate as compared to patients who received an ICD only. Screening for eligibility of BV pacing may be considered in patients with CHF scheduled for ICD implantation.
S G Molhoek; J J Bax; L van Erven; P Steendijk; E E van der Wall; M J Schalij
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of heart failure     Volume:  5     ISSN:  1388-9842     ISO Abbreviation:  Eur. J. Heart Fail.     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-11     Completed Date:  2003-12-11     Revised Date:  2011-06-08    
Medline Journal Info:
Nlm Unique ID:  100887595     Medline TA:  Eur J Heart Fail     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  315-7     Citation Subset:  IM    
Dept of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
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MeSH Terms
Cardiac Pacing, Artificial*
Defibrillators, Implantable*
Eligibility Determination*
Follow-Up Studies
Heart Failure / mortality,  physiopathology,  therapy
Heart Ventricles / physiopathology,  surgery
Middle Aged
Netherlands / epidemiology
Pacemaker, Artificial
Severity of Illness Index
Stroke Volume / physiology
Survival Analysis
Treatment Outcome
Ventricular Dysfunction, Left / mortality,  physiopathology,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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