Document Detail

Elevation of pancreatic enzymes in gallbladder bile associated with heterotopic pancreas. A case report and review of the literature.
MedLine Citation:
PMID:  22406610     Owner:  NLM     Status:  In-Data-Review    
CONTEXT: This is the first report associating heterotopic pancreas in the gallbladder and elevated pancreatic enzymes in bile.
CASE REPORT: A 60-year-old woman underwent abdominal ultrasonography at a medical check-up, revealing a nodular protrusion at the neck of the gallbladder. It seemed likely to be a lymph node, but we could not exclude the possibility of gallbladder cancer. In order to make a correct diagnosis, laparoscopic cholecystectomy was successfully performed. Pathological examination revealed heterotopic pancreatic tissue in the gallbladder wall. In addition, we detected elevated levels of amylase and lipase in gallbladder bile.
CONCLUSIONS: Preoperative diagnosis of heterotopic pancreas in the gallbladder is difficult. However, an increase of pancreatic enzymes in gallbladder bile may potentially play an important role in the occurrence of acalculous cholecystitis and biliary cancer. We need more accumulation of cases to know the true significance of this anomaly.
Asahi Sato; Masaji Hashimoto; Kazunari Sasaki; Masamichi Matsuda; Goro Watanabe
Publication Detail:
Type:  Journal Article     Date:  2012-03-10
Journal Detail:
Title:  JOP : Journal of the pancreas     Volume:  13     ISSN:  1590-8577     ISO Abbreviation:  JOP     Publication Date:  2012  
Date Detail:
Created Date:  2012-03-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101091810     Medline TA:  JOP     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  235-8     Citation Subset:  IM    
Department of Digestive Surgery, Toranomon Hospital. Tokyo, Japan.
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