Document Detail


Elevated total and isoenzyme forms of acid phosphatase in falciparum malaria.
MedLine Citation:
PMID:  16439336     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The activities of total serum acid phosphatase (E.C. 3.1.3.2) and of two of its isoenzymes, tartrate-resistant acid phosphatase and erythrocyte-specific acid phosphatase were measured in 109 adult male and female patients presenting acute falciparum malaria infection, and a normal, healthy control group comprised of 82 subjects. All the three forms of acid phosphatase were found to be significantly (p<0.05) higher during infection as compared to their activity in the control group. This result suggests that the measurement of acid phosphatase, particularly the erythrocyte isoenzyme, in serum could be potentially used as a biomarker of acute falciparum malaria infection.
Authors:
Ibrahim H Garba; Donatien Gatsing; Gregory Ubom
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Publication Detail:
Type:  Journal Article     Date:  2006-01-18
Journal Detail:
Title:  Comptes rendus biologies     Volume:  329     ISSN:  1631-0691     ISO Abbreviation:  C. R. Biol.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-01-27     Completed Date:  2006-03-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101140040     Medline TA:  C R Biol     Country:  France    
Other Details:
Languages:  eng     Pagination:  75-8     Citation Subset:  IM    
Affiliation:
Chemistry Programme, School of Science, Abubakar Tafawa Balewa University, PMB 0248 Bauchi, Nigeria. ihgarba2002@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Acid Phosphatase / blood*
Adolescent
Adult
Female
Humans
Isoenzymes / blood
Malaria, Falciparum / enzymology*
Male
Middle Aged
Nigeria
Chemical
Reg. No./Substance:
0/Isoenzymes; EC 3.1.3.2/Acid Phosphatase

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