Document Detail


Elevated static compliance of the total respiratory system: early predictor of weaning unsuccess in severed COPD patients mechanically ventilated.
MedLine Citation:
PMID:  7665749     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess in a group of COPD patients mechanically ventilated for an episode of acute respiratory failure the respiratory mechanics with a simple and non invasive method at the bedside in order to evaluate if these parameters may be predictive of weaning failure or success.
DESIGN: A prospective study.
SETTING: Intensive care and intermediate intensive care units.
PATIENTS: 23 COPD patients ventilated for acute respiratory failure and studied within 24 hours from intubation.
METHODS: Using end-expiratory and end-inspiratory airway occlusion technique, we measured PEEPi, static compliance of the respiratory system (Crs, st) maximum respiratory resistance (Rrsmax) and minimum respiratory resistance (Rrsmin).
MEASUREMENTS AND RESULTS: The weaned group (A) and the not weaned group (B) were not different regarding to static PEEPi (group A 8.5 +/- 4.0 vs group B 8.9 +/- 2.6 cmH2O), TO Rrsmax (22.4 +/- 5.3 versus 22.2 +/- 9.0 cmH2O/1/s) and to Rrsmin (17.6 +/- 5.5 versus 17.9 +/- 8.0 cmH2O/1/s), while a significant difference (p < 0.001) has been found in Cst, rs (62.7 +/- 17.% versus 111.6 +/- 18.0 ml/cm H2O). The threshold value of 88.5 ml/cmH2O was identified by discriminant analysis and provided the best separation between the two groups, with a sensitivity of 0.85 and a specificity of 0.87.
CONCLUSION: Cst, rs measured non invasively in the first 24 h from intubation, provided a good separation between the patients who were successfully weaned and those who failed.
Authors:
E Zanotti; F Rubini; G Iotti; A Braschi; A Palo; C Bruschi; C Fracchia; S Nava
Related Documents :
19619179 - The other side of injustice: when unfair procedures increase group-serving behavior.
16809989 - Intraoperative tidal volume as a risk factor for respiratory failure after pneumonectomy.
20177689 - Neoadjuvant chemoradiotherapy, sepsis and neutrophil levels following radical excision ...
15563699 - Readmission rates and life threatening events in copd survivors treated with non-invasi...
23749219 - Factors influencing the residual rib hump after posterior spinal fusion for adolescent ...
7963209 - Prognosis-based futility guidelines: does anyone win? support investigators. study to u...
24795499 - The effects of injury prevention warm-up programmes on knee strength in male soccer pla...
17198059 - Short bowel syndrome: current medical and surgical trends.
12356209 - Cerebral volume changes in multiple sclerosis patients treated with high-dose intraveno...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Intensive care medicine     Volume:  21     ISSN:  0342-4642     ISO Abbreviation:  Intensive Care Med     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-10-12     Completed Date:  1995-10-12     Revised Date:  2014-07-29    
Medline Journal Info:
Nlm Unique ID:  7704851     Medline TA:  Intensive Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  399-405     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acute Disease
Aged
Airway Resistance
Discriminant Analysis
Female
Humans
Lung Compliance*
Lung Diseases, Obstructive / complications*
Male
Middle Aged
Positive-Pressure Respiration, Intrinsic / diagnosis
Predictive Value of Tests
Prospective Studies
Respiratory Insufficiency / etiology,  physiopathology,  therapy*
Treatment Failure
Ventilator Weaning*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Limitations of oxygen transport to the cell.
Next Document:  Respiratory mechanics by least squares fitting in mechanically ventilated patients: applications dur...