Document Detail

Elevated maternal serum alpha-fetoprotein (MSAFP): interpretation and follow-up.
MedLine Citation:
PMID:  2456869     Owner:  NLM     Status:  MEDLINE    
Maternal serum alpha-fetoprotein screening should be offered to all patients as a routine component of prenatal care. The benefits of MSAFP screening have far exceeded early expectations. This technology not only provides an efficient and cost-effective method of screening for neural tube defects that is applicable to all pregnancies but also provides the physician with important information relevant to other complications of pregnancy. Our knowledge of variables affecting MSAFP levels measured during pregnancy is rapidly evolving and further refinements in the application of MSAFP screening will almost certainly occur. Such refinements can only serve to extend the benefits of this new and very valuable technology in improving the health and well-being of mothers and infants.
B K Burton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical obstetrics and gynecology     Volume:  31     ISSN:  0009-9201     ISO Abbreviation:  Clin Obstet Gynecol     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-09-22     Completed Date:  1988-09-22     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0070014     Medline TA:  Clin Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  293-305     Citation Subset:  IM    
Department of Pediatrics, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC 27103.
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MeSH Terms
Amniotic Fluid / metabolism
Fetal Diseases / diagnosis*,  epidemiology
Follow-Up Studies
Mass Screening
Neural Tube Defects / diagnosis*,  epidemiology
Pregnancy / blood
Prenatal Diagnosis*
alpha-Fetoproteins / metabolism*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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