| Elevated concentration of 5-hydroxytryptamine in ultrafiltrate of human liver vein plasma after infusion of amino acids. | |
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MedLine Citation:
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PMID: 3227956 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Intragastric infusion of amino acids causes the release from the liver of a factor with stimulatory effect on smooth muscle. The effect of liver vein plasma ultrafiltrate was tested on isolated preparations of rat fundus. The ultrafiltrates collected after amino acid infusion had a 3-5 times higher stimulatory effect on smooth muscle contraction than those collected from control plasma. The active principle was isolated, purified by different chromatographic procedures and identified as 5-hydroxytryptamine (serotonin). No other compound with contractile effect on smooth muscle was detected. |
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Authors:
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L Zimmerman; A Alvestrand; J Bergström |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta physiologica Scandinavica Volume: 134 ISSN: 0001-6772 ISO Abbreviation: Acta Physiol. Scand. Publication Date: 1988 Nov |
Date Detail:
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Created Date: 1989-04-06 Completed Date: 1989-04-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370362 Medline TA: Acta Physiol Scand Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 399-403 Citation Subset: IM |
Affiliation:
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Department of Renal Medicine, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Amino Acids / administration & dosage* Female Hepatic Veins Humans Male Muscle Contraction / drug effects Muscle, Smooth / drug effects Serotonin / isolation & purification*, pharmacology Ultrafiltration |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 50-67-9/Serotonin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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