Document Detail


Elevated central venous pressure: a consequence of exercise training-induced hypervolemia?
MedLine Citation:
PMID:  1996713     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Resting blood volumes and arterial and central venous pressures (CVP) were measured in 14 men before and after exercise training to determine whether training-induced hypervolemia is accompanied by a change in total vascular capacitance. In addition, resting levels of plasma arginine vasopressin (AVP), atrial natriuretic peptide (ANP), aldosterone (Ald), and norepinephrine (NE) were measured. The same measurements were conducted in seven subjects who did not undergo exercise and acted as controls. Exercise training consisted of 10 wk of controlled cycle exercise for 30 min/day, 4 days/wk at 75-80% of maximal O2 uptake (VO2max). A training effect was verified by a 20% increase in VO2max, a resting bradycardia, and a 9% increase in blood volume. Mean arterial blood pressure was unaltered by exercise training, but resting CVP increased by 16% (P less than 0.05). The percent change in blood volume from before to after training was linearly related to the percent change in CVP (r = 0.903, P less than 0.05). As a consequence of elevations in both blood volume and CVP, the volume-to-pressure ratio was unchanged after exercise training. Plasma AVP, ANP, Ald, and NE were unaltered. Our results indicate that elevated CVP is a consequence of training-induced hypervolemia without alteration in total effective venous capacitance.
Authors:
V A Convertino; G W Mack; E R Nadel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of physiology     Volume:  260     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-03-22     Completed Date:  1991-03-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  R273-7     Citation Subset:  IM; S    
Affiliation:
Biomedical Operations and Research Office, National Aeronautics and Space Administration, Kennedy Space Center, Florida 32899.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Pressure
Blood Volume*
Central Venous Pressure*
Humans
Male
Oxygen Consumption
Physical Education and Training*
Physical Endurance
Investigator
Investigator/Affiliation:
V A Convertino / KSC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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