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Elevated aldosterone levels in patients with androgenetic alopecia.
MedLine Citation:
PMID:  19519833     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: There is reported to be an elevated prevalence of hypertension among patients with androgenetic alopecia (AGA), and it has been proposed that both phenomena may be explained by the presence of hyperaldosteronism. However, no data on aldosterone levels in patients with AGA have been published to date. OBJECTIVES: The objective of this pilot study was to evaluate aldosterone levels and the presence of hypertension in patients with AGA and in healthy controls. METHODS: This case-control study included 40 patients with AGA and 40 healthy controls from the Dermatology Department of San Cecilio Hospital, Granada, Spain. RESULTS: Patients with AGA showed significantly higher systolic blood pressure values (136.23 vs. 124.10 mmHg, P = 0.01) and aldosterone levels (197.35 vs. 133.71 pg mL(-1), P = 0.007) vs. controls. CONCLUSION: The elevated aldosterone values in these patients may contribute, together with other mechanisms, to the development of AGA and may also explain the higher prevalence of hypertension. Blood pressure screening of patients with AGA will permit earlier diagnosis of an unknown hypertension and initiation of appropriate treatment.
Authors:
S Arias-Santiago; M T Gutiérrez-Salmerón; L Castellote-Caballero; R Naranjo-Sintes
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Publication Detail:
Type:  Journal Article     Date:  2009-06-09
Journal Detail:
Title:  The British journal of dermatology     Volume:  161     ISSN:  1365-2133     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1196-8     Citation Subset:  IM    
Affiliation:
Dermatology Unit, San Cecilio University Hospital, Granada 18012, Spain. salvadorarias@hotmail.es
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