Document Detail

Elevated Myocardial Enzymes and Natriuretic Peptides in Anorexia Nervosa: Prototypic Condition for the Pathophysiology of Cachexia?
MedLine Citation:
PMID:  21757899     Owner:  NLM     Status:  Publisher    
We report on a patient suffering from chronic anorexia nervosa who in the course of treatment showed elevated high-sensitive troponin T, creatine kinase and most markedly N-terminal pro-brain natriuretic peptide (NT-proBNP). Elevated enzymes improved significantly throughout the course of treatment without cardiac specific medication but exceeded the normal range for weeks. Abnormally high myocardial enzymes and NT-proBNP in cachectic anorectic patients might resemble conditions of cardiac cachexia. A review of the available literature is provided. Further research is required to explain the pathophysiological meaning of the abnormal laboratory findings.
Arne Zastrow; Johanna Wolf; Evangelos Giannitsis; Hugo Katus; Wolfgang Herzog; Hans-Christoph Friederich; Christina Mussler
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-14
Journal Detail:
Title:  Cardiology     Volume:  118     ISSN:  1421-9751     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  256-259     Citation Subset:  -    
Copyright Information:
Copyright © 2011 S. Karger AG, Basel.
Department of General Internal Medicine and Psychosomatics, University of Heidelberg, Heidelberg, Germany.
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