Document Detail


Elevated Anterior Compartment Pressure in the Leg After Creatine Supplementation: A Controlled Case Report.
MedLine Citation:
PMID:  12937519     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To report abnormal changes in lower leg anterior compartment pressure in 1 subject who consumed creatine as a dietary supplement. BACKGROUND: The subject received creatine at a dosage of 0.3 g.kg body mass(-1).d(-1) for 6 days, followed by 0.03 g.kg body mass(-1).d(-1) for 28 days. Thereafter, the subject consumed no supplement for 21 days. Compartment pressure was measured pre-exercise and for 15 minutes postexercise after a treadmill run for 20 minutes at 80% of VO(2) max before supplementation and after 6 and 34 days of supplementation. DIFFERENTIAL DIAGNOSIS: Normally, resting anterior compartment pressure is less than 15 mm Hg, whereas postexercise pressure is below 30 to 35 mm Hg. Creatine supplementation for 6 days dramatically increased pressure at rest (31 mm Hg) and at 1 minute (67 mm Hg), 5 minutes (35 mm Hg), 10 minutes (28 mm Hg), and 15 minutes (26 mm Hg) postexercise. Pressure remained high at rest (35 mm Hg) and at 1 minute (109 mm Hg), 5 minutes (90 mm Hg), 10 minutes (87 mm Hg), and 15 minutes (69 mm Hg) postexercise after 34 days of supplementation. TREATMENT: The subject stopped taking creatine for 21 days. Compartment pressure was measured at rest and after exercise after 7 and 21 days with no supplementation. Anterior compartment pressure decreased after cessation of creatine supplementation. However, pressures were elevated at 7 days postsupplementation at rest (26 mm Hg) and at 1 minute (112 mm Hg), 5 minutes (58 mm Hg), 10 minutes (40 mm Hg), and 15 minutes (30 mm Hg) postexercise. Pressures at 21 days postsupplementation remained high at rest (24 mm Hg) and at 1 minute (64 mm Hg), 5 minutes (42 mm Hg), 10 minutes (27 mm Hg), and 15 minutes (27 mm Hg) postexercise. CONCLUSION: These data indicate that creatine supplementation can substantially increase anterior compartment pressure in the leg.
Authors:
Jeffrey A. Potteiger; Jeffrey C. Randall; Cynthia Schroeder; Lawrence M. Magee; Matthew W. Hulver
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Journal of athletic training     Volume:  36     ISSN:  1938-162X     ISO Abbreviation:  J Athl Train     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2003-Aug-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9301647     Medline TA:  J Athl Train     Country:  -    
Other Details:
Languages:  ENG     Pagination:  85-88     Citation Subset:  -    
Affiliation:
University of Kansas, Lawrence, KS.
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