| Elemental analysis of femoral bone from patients with fractured neck of femur or osteoarthrosis. | |
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MedLine Citation:
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PMID: 8833209 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The elemental composition of bone has been determined by inductively coupled atomic emission and mass spectrometry to test the hypothesis that changes in major or minor elemental concentrations may contribute to the risk of fracture. Femoral bone was obtained from patients at operation for the treatment of fracture and compared with that of patients with osteoarthrosis and a necropsy control group. The data suggest that there are no major differences in bone elemental composition in patients with fractures compared with the control group. Bone adjacent to joints with osteoarthrosis tends to be less mineralized (per unit trabecular bone volume) than control bone and bone from fracture patients, and has significantly lower concentrations of boron, lead and, zinc. These observations may reflect the more rapid turnover of bone close to the arthritic joint. |
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Authors:
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T R Helliwell; S A Kelly; H P Walsh; L Klenerman; J Haines; R Clark; N B Roberts |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Bone Volume: 18 ISSN: 8756-3282 ISO Abbreviation: Bone Publication Date: 1996 Feb |
Date Detail:
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Created Date: 1997-05-29 Completed Date: 1997-05-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8504048 Medline TA: Bone Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 151-7 Citation Subset: IM |
Affiliation:
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Department of Pathology, University of Liverpool, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Bone and Bones / chemistry* Female Femoral Neck Fractures / metabolism, pathology* Humans Male Mass Spectrometry / methods* Middle Aged Osteoarthritis / metabolism, pathology* Sensitivity and Specificity Trace Elements / analysis* |
| Chemical | |
Reg. No./Substance:
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0/Trace Elements |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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