Document Detail


Elejalde syndrome--a case report.
MedLine Citation:
PMID:  16969863     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Elejalde syndrome (McKusick 200995), also known as acrocephalopolydactylous dysplasia, is a rare condition. We describe a sixth patient with this syndrome which is characterized by craniosynostosis and hyperproliferation of fibroblasts in many tissues including skin, liver, kidney, and pancreas. The cause of the syndrome is the homozygous state of an autosomal recessive mutation. We present a hypothesis that Elejalde syndrome might be associated with an inactivating FGFR gene mutation.
Authors:
Eva Silhánová; Pavlína Plevová; Romuald Curík; Ivo Kaspercík; Anna Krepelová
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of medical genetics. Part A     Volume:  140     ISSN:  1552-4825     ISO Abbreviation:  Am. J. Med. Genet. A     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-28     Completed Date:  2006-12-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235741     Medline TA:  Am J Med Genet A     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2223-6     Citation Subset:  IM    
Copyright Information:
(c) 2006 Wiley-Liss, Inc.
Affiliation:
Department of Medical Genetics, Faculty Hospital, Ostrava, Czech Republic.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / genetics*,  pathology*,  radiography
Craniosynostoses / genetics*,  pathology*,  radiography
Female
Humans
Infant, Newborn
Kidney / pathology
Liver / pathology
Pancreas / pathology
Skin / pathology
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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