| Electrospinning of polysaccharides for regenerative medicine. | |
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MedLine Citation:
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PMID: 19643155 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Electrospinning techniques enable the production of continuous fibers with dimensions on the scale of nanometers from a wide range of natural and synthetic polymers. The number of recent studies regarding electrospun polysaccharides and their derivatives, which are potentially useful for regenerative medicine, is increasing dramatically. However, difficulties regarding the processibility of the polysaccharides (e.g., poor solubility and high surface tension) have limited their application. In this review, we summarize the characteristics of various polysaccharides such as alginate, cellulose, chitin, chitosan, hyaluronic acid, starch, dextran, and heparin, which are either currently being used or have potential to be used for electrospinning. The recent progress of nanofiber matrices electrospun from polysaccharides and their biomedical applications in tissue engineering, wound dressings, drug delivery, and enzyme immobilization are discussed. |
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Authors:
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Kuen Yong Lee; Lim Jeong; Yun Ok Kang; Seung Jin Lee; Won Ho Park |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-07-28 |
Journal Detail:
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Title: Advanced drug delivery reviews Volume: 61 ISSN: 1872-8294 ISO Abbreviation: Adv. Drug Deliv. Rev. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8710523 Medline TA: Adv Drug Deliv Rev Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1020-32 Citation Subset: IM |
Affiliation:
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Department of Bioengineering, Hanyang University, Seoul, South Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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