Document Detail

Electroretinography of short-wavelength-sensitive cones with a LED built-in electrode and its normal values.
MedLine Citation:
PMID:  12737509     Owner:  NLM     Status:  MEDLINE    
To record electroretinograms (ERG) produced by short-wavelength-sensitive cone mechanisms (SWS-cone ERG), the authors used three kinds (blue, green, and red) of light-emitting diode (LED) which were built into a contact lens electrode assembly. The LEDs were used as both stimulus and background light sources. ERG was recorded using blue LED after 10 min of yellow light adaptation produced by green and red LEDs. Duration of photo-stimulation was either 2 or 100 ms. ERG recorded in normal human subjects showed two positive waves with 2 ms photo-stimulation. Amplitude of the former positive wave (b1-wave) was attenuated when the luminance of yellow background increased, and the latter positive wave (b2-wave) was attenuated when the color of photo-stimulation was green or red. These findings suggest that middle-wavelength-sensitive and long-wavelength-sensitive cone mechanisms generated the former positive wave (b1-wave) and SWS-cone mechanisms generated the latter positive wave (b2-wave). Ratio of b2-wave-amplitude to b1-wave-amplitude with 2 ms photo-stimulation measured on 39 normal subjects ranged from 0.5 to 2.0. It was concluded that this three-colored LED built-in electrode was useful for recording SWS-cone ERG.
Kazuki Kuniyoshi; Naoki Uno; Motohiro Irifune; Yoshikazu Shimomura
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Documenta ophthalmologica. Advances in ophthalmology     Volume:  106     ISSN:  0012-4486     ISO Abbreviation:  Doc Ophthalmol     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-05-09     Completed Date:  2003-06-09     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370667     Medline TA:  Doc Ophthalmol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  311-8     Citation Subset:  IM    
Department of Ophthalmology, Kinki University School of Medicine, Ohno-Higashi, Osaka-Sayama City, Osaka 589, Japan.
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MeSH Terms
Contact Lenses
Electroretinography / methods*
Middle Aged
Radio Waves
Retinal Cone Photoreceptor Cells / physiology*

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