| Electrophysiological and morphological development of the inner ear in Belgian Waterslager canaries. | |
| | |
MedLine Citation:
|
PMID: 20638464 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Belgian Waterslager (BW) canaries have an inherited hearing loss due to missing and abnormal hair cells, but it is unclear whether the loss is congenital or developmental. We used auditory brainstem responses and scanning electron microscopy to describe the development of auditory sensitivity and hair cell abnormalities in BW and non-BW canaries. In both strains, adult ABR thresholds were higher than behavioral thresholds, but BW canaries exhibited higher thresholds than non-BW canaries across all frequencies. Immediately post-hatch, ABR thresholds and hair cell numbers were similar in both strains. Two weeks later, thresholds were significantly higher in BW canaries, and hair cell number progressively decreased as the birds aged. These data show that in BW canaries: the peripheral auditory system is functionally similar to non-BW canary from hatch to 2 weeks, ABR thresholds improve during this developmental period, actually becoming better than those of adults, but then worsen as the bird continues to age. Hair cell number and appearance is similar to non-BW canaries at hatch but progressively declines after 30 days of age. These data show that the hearing loss characteristic of BW canaries is, at least in part, developmental and is established by the time song learning begins. |
| | |
Authors:
|
Elizabeth F Brittan-Powell; Robert J Dooling; Brenda Ryals; Otto Gleich |
Related Documents
:
|
7477044 - Effects of aluminum chloride on the nucleus and nucleolus in root tip cells of hordeum ... 10917164 - Cytokeratin expression of apocrine and eccrine poromas with special reference to its ex... 16155904 - Isolation and culture of hair cell progenitors from postnatal rat cochleae. 17450124 - A chromatin link that couples cell division to root epidermis patterning in arabidopsis. 7477044 - Effects of aluminum chloride on the nucleus and nucleolus in root tip cells of hordeum ... 3162674 - Relationship between membrane sterol composition and responsiveness to 12-o-tetradecano... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural Date: 2010-07-16 |
Journal Detail:
|
Title: Hearing research Volume: 269 ISSN: 1878-5891 ISO Abbreviation: Hear. Res. Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-09-06 Completed Date: 2010-12-28 Revised Date: 2012-05-07 |
Medline Journal Info:
|
Nlm Unique ID: 7900445 Medline TA: Hear Res Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 56-69 Citation Subset: IM |
Affiliation:
|
Department of Psychology, University of Maryland, College Park, MD 20742, USA. bbrittanpowell@psyc.umd.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acoustic Stimulation Aging / pathology, physiology* Animals Auditory Threshold / physiology Canaries / growth & development*, physiology* Ear, Inner / growth & development*, physiopathology* Electrophysiological Phenomena / physiology* Evoked Potentials, Auditory, Brain Stem / physiology Hair Cells, Auditory, Inner / pathology, physiology, ultrastructure Hearing Loss / physiopathology* Microscopy, Electron, Scanning Models, Animal Reaction Time / physiology |
| Grant Support | |
ID/Acronym/Agency:
|
DC-001372/DC/NIDCD NIH HHS; P30 DC004664-03/DC/NIDCD NIH HHS; R01 DC001372-10/DC/NIDCD NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: N-Acetyl-cysteine against noise-induced temporary threshold shift in male workers.
Next Document: Effects of prenatal stress and exercise on dentate granule cells maturation and spatial memory in ad...