Document Detail

Electrophysiological monitoring of cochlear function as a non-invasive method to assess intracranial pressure variations.
MedLine Citation:
PMID:  22327678     Owner:  NLM     Status:  In-Process    
The "cochlear" aqueduct is a narrow channel connecting the subarachnoid and intralabyrinthine spaces. Through this communication, cerebrospinal fluid (CSF) pressure variations are transmitted to the intralabyrinthine space and modify the impedance of the ear. Distortion-product otoacoustic emissions (DPOAE) are sounds emitted by cochlear sensory cells in response to sonic stimulation. Cochlear microphonic potentials (CMP) express the electrophysiological activity of cochlear sensory cells. At 1 kHz, the phase of DPOAE and CMP varies according to the impedance of the ear and thus to intracranial pressure (ICP) variations. DPOAE and CMP have been shown to strictly follow ICP variations produced during infusion tests performed in the diagnosis of chronic hydrocephalus. DPOAE and CMP recordings appear to be valuable tools for monitoring ICP non-invasively.
Laurent Sakka; Aurélie Thalamy; Fabrice Giraudet; Thierry Hassoun; Paul Avan; Jean Chazal
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neurochirurgica. Supplement     Volume:  114     ISSN:  0065-1419     ISO Abbreviation:  Acta Neurochir. Suppl.     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100962752     Medline TA:  Acta Neurochir Suppl     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  131-4     Citation Subset:  IM    
Department of Neurosurgery, Clermont University, Clermont-Ferrand, France.
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