Document Detail


Electrophysiological characteristic of a patient exhibiting the short-coupled variant of torsade de pointes.
MedLine Citation:
PMID:  11455519     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 41-year-old man was admitted because of syncope. The electrocardiogram showed torsade de pointes (Tdp) with no long QT interval and the coupling interval of the initial beat of Tdp was 240 ms. Heterogeneity of ventricular refractoriness was observed together with shortness of the effective refractory period measured at the right ventricular inflow site where the paced QRS morphology was the same as that of the initial beat of Tdp. Verapamil could suppress frequent ventricular premature complexes with a short coupling interval, which lead to Tdp. Polymorphic ventricular tachycardia was induced by triple ventricular extrastimuli. A pure potassium channel blocker was successful in inhibiting polymorphic ventricular tachycardia inducibility by prolongation of refractoriness. These results suggested that triggered ventricular premature complexes may be represent the initiating mechanism, whereas the shortness of local refractory period and heterogeneity of ventricular refractoriness may play a role in the development and the maintenance of the Tdp.
Authors:
T Shiga; M Shoda; N Matsuda; Y Fuda; N Hagiwara; S Ohnishi; A Watanabe; H Kasanuki
Related Documents :
1810689 - The monophasic action potential in clinical cardiology.
8701769 - Effects of panax notoginseng saponin rg1 on cardiac electrophysiological properties and...
18952549 - Cardiac repolarization analysis using the surface electrocardiogram.
3993529 - Prevention of ventricular fibrillation by dextrorotatory sotalol in a conscious canine ...
8859929 - Electrophysiological effects of clentiazem, a new ca2+ antagonist, on rabbit hearts.
8256749 - How to measure the qt interval--what is normal?
10498129 - Comparison of dobutamine echocardiography, dobutamine sestamibi, and rest-redistributio...
2095829 - Inotropic interventions during myocardial "stunning" in the pig.
19027779 - Dispersions of repolarization and ventricular arrhythmogenesis: lessons from animal mod...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  34     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-07-16     Completed Date:  2001-09-13     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  271-5     Citation Subset:  IM    
Affiliation:
Department of Cardiology, The Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Japan. mshiga@hij.twmu.ac.jp
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Arrhythmia Agents / pharmacology
Electrocardiography*
Electrophysiologic Techniques, Cardiac
Heart Conduction System / physiopathology*
Humans
Male
Torsades de Pointes / diagnosis,  physiopathology*
Ventricular Premature Complexes / diagnosis,  physiopathology*
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Unusual ECG responses to exercise stress testing.
Next Document:  Urban renal disease: reflections of an urban nephrologist.