Document Detail


Electrophysiologic properties of atrial muscle in paroxysmal atrial fibrillation.
MedLine Citation:
PMID:  2480704     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The electrophysiologic properties of atrial muscle were studied by programmed atrial stimulation in 42 patients with paroxysmal atrial fibrillation (PAF) and in 53 control patients without PAF. Single premature atrial stimulation was given at the right atrial appendage following 8 basic stimuli with a basic cycle length of 500 ms. Repetitive atrial firing (RAF) was defined as the occurrence of 2 or more successive premature atrial activations following single premature atrial stimulation. Fragmented atrial activity (FAA) was defined as an increase by more than 75% of the duration of the atrial electrogram in response to a single premature stimulation. Interatrial conduction delay was defined as an increase of the conduction time by more than 50 ms in response to a single premature stimulation. RAF was induced in 26 of 42 patients (61.9%) with PAF and in 14 of 53 control patients (26.4%). FAA and interatrial conduction delay were elicited in 69.0 and 80.9% of patients with PAF and in 34.0 and 56.6% of control patients, respectively. In 16 patients with PAF in whom RAF was not induced, FAA developed in 11 patients (68.8%). In 88.1% of 42 patients with PAF and in 41.5% of 53 controls, RAF or FAA, or both, were elicited by atrial premature stimulation. It is concluded that the incidence of RAF and FAA were significantly higher in patients with PAF than in the control group, and the induction of RAF or FAA, or both, was closely related to the vulnerability of the atrial muscle to atrial fibrillation.
Authors:
K Hashiba; M Tanigawa; M Fukatani; A Shimizu; A Konoe; M Kadena; M Mori
Related Documents :
9826854 - Uncommon atrial flutter: characteristics, mechanisms, and results of ablative therapy.
11428284 - Diagnostic accuracy of transesophageal echocardiography for detection of atrial masses.
20538554 - The association of beta-fibrinogen 455 g/a gene polymorphism with left atrial thrombus ...
19474574 - Incidence of spontaneous echocontrast, 'sludge' and thrombi before cardioversion in pat...
16886894 - Il-1b and il-1rn gene polymorphisms in rheumatoid arthritis: relationship with protein ...
24574834 - Is propofol safe when administered to cirrhotic patients during sedative endoscopy?
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  64     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-01-17     Completed Date:  1990-01-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  20J-23J     Citation Subset:  AIM; IM    
Affiliation:
Third Department of Internal Medicine, Nagasaki University School of Medicine, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Atrial Fibrillation / physiopathology*
Cardiac Complexes, Premature / physiopathology
Electric Stimulation
Electrophysiology
Heart / physiopathology*
Heart Atria
Heart Conduction System / physiopathology
Humans
Reaction Time

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Classification of antiarrhythmic drugs based on ventricular fibrillation threshold.
Next Document:  Ionic mechanisms of the depression of automaticity and conduction in the rabbit atrioventricular nod...