Document Detail


Electrophysiologic and pathologic correlations in two cases of chronic second degree atrioventricular block with left bundle branch block.
MedLine Citation:
PMID:  125157     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study concerns two cases of chronic 2 degrees atrioventricular (A-V) block with left bundle branch block (LBBB). Pathological studies included serial section of the conduction systems. Case 1 had type I 2 degrees block with LBBB. Electrophysiological studies revealed type I 2 degrees block proximal to the His bundle recording site and a prolonged H-V interval (60 msec). Pathologically there was a moderate to marked fibrosis of the approaches to the A-V node and of the A-V node, marked fibrosis of the left bundle branch, and moderate involvement of the right bundle branch. The changes proximal to the His bundle were more marked than the changes distal to this bundle. Case 2 had type II and 2:1 2 degrees A-V block with LBBB. Electrophysiologically the site of block was distal to the His bundle recording site, and there was a prolonged A-V node and severe involvement of both bundle branches. The changes distal to the His bundle were more severe than the changes proximal to the His bundle. This study reveals that the electrophysiologic data more closely approximated the pathologic findings than did surface electrocardiographic data alone. It also emphasizes that there may be multiple sites of disease in chronic 2 degrees block with bundle branch block.
Authors:
S Bharati; M Lev; R C Dhingra; R Chuquimia; W D Towne; K M Rosen
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Circulation     Volume:  52     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1975 Aug 
Date Detail:
Created Date:  1975-11-08     Completed Date:  1975-11-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  221-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Autopsy
Bundle of His / physiopathology
Bundle-Branch Block / complications,  physiopathology*
Cardiomegaly / pathology,  physiopathology
Electrocardiography
Electrophysiology
Heart Block / complications,  physiopathology*
Heart Conduction System / physiopathology
Humans
Male
Microscopy, Electron
Middle Aged
Myocardium / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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