Document Detail


Electrophysiologic evaluations of thymectomy in myasthenia gravis. Preliminary findings.
MedLine Citation:
PMID:  945508     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Electric testing was performed in 106 myasthenia gravis patients before and after transcervical thymectomy. Twenty-nine were followed for 3 to 24 months. Results were correlated with thymic pathology, duration of disease, age at operation, and follow-up clinical status. Electric improvement was significantly greater in patients without thymic germinal centers or with only rare to occasional germinal centers, in patients operated on within 1 year after onset of symptoms, and in patients under age 30. Electric improvement immediately after thymectomy heralded later clinical improvement in those patients without germinal centers or with rare to occasional germinal centers. Electric-clinical correlations were excellent in patients with longer follow-up. Serial electric testing provides an objective evaluation of the patients' clinical status post-thymectomy.
Authors:
S H Horowitz; G Genkins; A E Papatestas; P Kornfeld
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Neurology     Volume:  26     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1976-08-23     Completed Date:  1976-08-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  615-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Evoked Potentials
Female
Follow-Up Studies
Humans
Male
Middle Aged
Myasthenia Gravis / physiopathology,  therapy*
Neural Conduction
Peripheral Nerves / physiopathology
Prognosis
Thymectomy*
Thymus Gland / pathology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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