| Electrophysiologic effects of magnesium sulfate infusion in patients with cardiac conduction defects. | |
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MedLine Citation:
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PMID: 1506602 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the electrocardiographic and electrophysiologic effects of magnesium (Mg) sulfate infusion in 25 normomagnesemic patients (16 men and 9 women, aged 22-74 years; mean +/- SD, 60.4 +/- 11.9) with different cardiac conduction impairments. Ten patients had chronic ischemic heart disease, two had idiopathic dilated cardiomyopathy, two had hypertensive heart disease, three had valvular heart disease, five had sclerodegenerative heart disease and three had no clinical evidence of cardiac disease. Five patients had trifascicular block [first degree atrioventricular (A-V) block+right bundle branch block (RBBB)+left anterior hemiblock (LAH)], eight had bifascicular block (6 RBBB+LAH, 2 first degree A-V block+RBBB), four had isolated first degree A-V block and eight had bundle branch block [5 RBBB, 3 left bundle branch block (LBBB)]. Before and during Mg infusion (50 mg/min/60 min) we evaluated the A-V (P-R), intraatrial (P-A), suprahisian (A-H), infrahisian (H-V) conduction times, electrical ventricular systole (Q-T), Q-T index (Q-Tc) intraventricular conduction time (QRS) and heart rate. At the end of infusion the P-R, P-A, A-H, H-V increased from 215.4 +/- 36.6, 33.6 +/- 9.1, 112.8 +/- 37.3, 69.0 +/- 12.8 ms to 217.6 +/- 37.1 (p less than 0.002), 33.8 +/- 9.4 (NS), 114.2 +/- 38.1 (p less than 0.005), 69.6 +/- 13.3 (NS) ms. QRS complex did not change (125 +/- 16.9 ms).(ABSTRACT TRUNCATED AT 250 WORDS) |
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Authors:
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F Perticone; R Ceravolo; R Costa; P L Mattioli |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American College of Nutrition Volume: 11 ISSN: 0731-5724 ISO Abbreviation: J Am Coll Nutr Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1992-09-24 Completed Date: 1992-09-24 Revised Date: 2008-06-23 |
Medline Journal Info:
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Nlm Unique ID: 8215879 Medline TA: J Am Coll Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 405-9 Citation Subset: IM |
Affiliation:
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Department of Medicina Sperimentale e Clinica, Medical School, University of Reggio, Catanzaro, Calabria, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cardiomyopathy, Dilated / physiopathology Coronary Disease / physiopathology Electrocardiography Electrophysiology Female Heart / drug effects, physiopathology Heart Block / physiopathology* Heart Conduction System / drug effects, physiopathology Heart Rate Heart Valve Diseases / physiopathology Humans Magnesium Sulfate / pharmacology*, therapeutic use Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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7487-88-9/Magnesium Sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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