| The Electroosmotic Flow (EOF). | |
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MedLine Citation:
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PMID: 19763462 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Controlling and manipulating liquids and analytes at the sub-millimeter scale is a challenge that frequently requires new methods to be developed. Indeed, scaling-down of traditional macroscopic ideas often fails. For instance, pumping liquids using pressure differences is often impractical and counterproductive because the resulting parabolic flow profile deforms sample zones. As the size of the system shrinks, the surface-to-volume ratio increases and interfacial effects become dominant. This actually opens new possibilities since the phenomenon of electroosmotic flow (EOF), wherein a fluid is made to move relative to a stationary charged boundary, can then be exploited to design efficient microfluidic devices. In this chapter, we review the fundamental principles of EOF as well as some of the methods used to coat channel walls and reduce the impact of EOF in situations where it would be unfavorable for the device performance. |
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Authors:
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Gary W Slater; Fr??d??ric Tessier; Katerina Kopecka |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Methods in molecular biology (Clifton, N.J.) Volume: 583 ISSN: 1940-6029 ISO Abbreviation: Methods Mol. Biol. Publication Date: 2010 |
Date Detail:
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Created Date: 2009-09-18 Completed Date: 2010-01-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9214969 Medline TA: Methods Mol Biol Country: United States |
Other Details:
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Languages: eng Pagination: 121-34 Citation Subset: IM |
Affiliation:
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Department of Physics, University of Ottawa, Ottawa, ON, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adsorption Coated Materials, Biocompatible / chemistry Electrochemistry / methods Electroosmosis* / methods Electrophoresis, Capillary / methods Hydrogen-Ion Concentration Microfluidics Models, Biological Polymers / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Coated Materials, Biocompatible; 0/Polymers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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