| Electron microscopy of Plasmodium vivax exoerythrocytic schizonts grown in vitro in a hepatoma cell line. | |
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MedLine Citation:
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PMID: 3010750 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Human hepatoma cells (HepG2-A16) have been shown to be useful for the growth of the exoerythrocytic stages of P. vivax. In order to determine whether the parasites grown in these cells are morphologically similar to those grown in vivo, we performed electron microscopy on the exoerythrocytic (EE) schizonts of P. vivax developed from sporozoites. This study showed for the first time that P. vivax EE schizonts within these cells closely resemble other plasmodial EE schizonts both in vivo and in vitro. |
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Authors:
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S Uni; M Aikawa; W E Collins; C C Campbell; M R Hollingdale |
Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 34 ISSN: 0002-9637 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 1985 Nov |
Date Detail:
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Created Date: 1986-06-18 Completed Date: 1986-06-18 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1017-21 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Carcinoma, Hepatocellular Cell Line Cell Membrane / ultrastructure Cell Nucleus / ultrastructure Cytoplasmic Granules / ultrastructure Humans Intracellular Membranes / ultrastructure Liver Neoplasms Microscopy, Electron Mitochondria / ultrastructure Plasmodium vivax / growth & development, ultrastructure* Vacuoles / ultrastructure |
| Grant Support | |
ID/Acronym/Agency:
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AI-19088/AI/NIAID NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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