| Electron beam CT versus 16-MDCT on the variability of repeated coronary artery calcium measurements in a variable heart rate phantom. | |
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MedLine Citation:
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PMID: 16177422 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: High reproducibility of coronary artery calcium (CAC) scoring is a key requirement for monitoring the progression of coronary atherosclerosis. The purposes of this study were to compare electron beam CT and 16-MDCT scanners in the variability of repeated CAC measurements and to assess the factors influencing this variability. MATERIALS AND METHODS: CAC models of different sizes attached to a cardiac phantom with a programmable variable heart rate were scanned three times, and interscan variability of the CAC measurement was calculated each time. For helical CT, different slice-thickness images of either retrospective ECG-gated or prospective ECG-triggering reconstruction were obtained. The detection of small amounts of calcium, variability of the Agatston score, and CAC measurement algorithms (Agatston, volume, and mass scores) were compared between CT scanners and protocols. RESULTS: All 1-mm-sized calcium models were detected on 0.625- and 1.25-mm helical CT, whereas some were missed on electron beam CT and 2.5-mm helical CT. Retrospective ECG-gated thin-slice helical CT showed the lowest variability. Reduction of variability by volume and mass scoring algorithms was less effective on 0.625- and 1.25-mm-thickness CT. CONCLUSION: Retrospective ECG-gated thin-slice helical CT has the potential to be a useful tool for monitoring coronary atherosclerosis. |
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Authors:
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Jun Horiguchi; Yun Shen; Yuji Akiyama; Nobuhiko Hirai; Kousuke Sasaki; Minoru Ishifuro; Tadashi Nakanishi; Katsuhide Ito |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 185 ISSN: 0361-803X ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-09-22 Completed Date: 2005-11-29 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 995-1000 Citation Subset: AIM; IM |
Affiliation:
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Department of Clinical Radiology, Hiroshima University Hospital, 1-2-3, Kasumi-cho, Minami-ku, Hiroshima 734-8551, Japan. horiguch@hiroshima-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Calcinosis / radiography* Coronary Artery Disease / radiography* Heart Rate / physiology Humans Phantoms, Imaging Reproducibility of Results Tomography Scanners, X-Ray Computed* Tomography, Spiral Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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