Document Detail


Electromagnetic pulses induce fluctuations in blood pressure in rats.
MedLine Citation:
PMID:  17487681     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To investigate the effects of exposure to electromagnetic pulses (EMP) on functional indices of the cardiovascular system in male Sprague-Dawley rats. MATERIALS AND METHODS: A tapered parallel plate Gigahertz Transverse Electromagnetic cell (GTEM cell) with a flared rectangular coaxial transmission line was used to expose the rats to EMP (0.5 pps, total 200 pulses and whole-body averaged specific absorption rate 50 mW/kg at 200 kV/m or 75 mW/kg at 400 kV/m). Concurrent sham-exposed animals were used as controls. Cardiovascular functions, namely, heart rate, and systolic, mean and diastolic blood pressures were measured immediately and up to 4 weeks post-exposure using a non-invasive tail-cuff photoelectric sensor sphygmomanometer. RESULTS: The heart rates in sham- and EMP-exposed rats were not significantly changed. In the exposed rats, increased systolic blood pressure (SBP) occurred at 0 h and decreased SBP occurred at 1 day and 3 days after exposure. Significantly higher diastolic blood pressure (DBP) was found at 0 h and significantly lower DBP was found at 12 h, 1 day, and 1 month after exposure. Significantly higher mean arterial pressure (MAP) was noted at 0 h and significantly lower MAP was noted at 1 day. CONCLUSIONS: Significant alterations in arterial blood pressure were observed in rats exposed to EMP exposure while heart rate was not altered.
Authors:
Bao-Feng Li; Guo-Zhen Guo; Dong-Qing Ren; Jing-Li; Ruo-Bing Zhang
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of radiation biology     Volume:  83     ISSN:  0955-3002     ISO Abbreviation:  Int. J. Radiat. Biol.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-09     Completed Date:  2007-07-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809243     Medline TA:  Int J Radiat Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  421-9     Citation Subset:  IM; S    
Affiliation:
Department of Radiation Medicine, Fourth Military Medical University, Shannxi Province, China.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Flow Velocity / physiology,  radiation effects*
Blood Pressure / physiology,  radiation effects*
Dose-Response Relationship, Radiation
Electromagnetic Fields*
Heart Rate / physiology,  radiation effects*
Male
Pulsatile Flow / physiology,  radiation effects*
Radiation Dosage
Rats
Rats, Sprague-Dawley
Whole-Body Irradiation / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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