| Electromagnetic pulses induce fluctuations in blood pressure in rats. | |
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MedLine Citation:
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PMID: 17487681 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To investigate the effects of exposure to electromagnetic pulses (EMP) on functional indices of the cardiovascular system in male Sprague-Dawley rats. MATERIALS AND METHODS: A tapered parallel plate Gigahertz Transverse Electromagnetic cell (GTEM cell) with a flared rectangular coaxial transmission line was used to expose the rats to EMP (0.5 pps, total 200 pulses and whole-body averaged specific absorption rate 50 mW/kg at 200 kV/m or 75 mW/kg at 400 kV/m). Concurrent sham-exposed animals were used as controls. Cardiovascular functions, namely, heart rate, and systolic, mean and diastolic blood pressures were measured immediately and up to 4 weeks post-exposure using a non-invasive tail-cuff photoelectric sensor sphygmomanometer. RESULTS: The heart rates in sham- and EMP-exposed rats were not significantly changed. In the exposed rats, increased systolic blood pressure (SBP) occurred at 0 h and decreased SBP occurred at 1 day and 3 days after exposure. Significantly higher diastolic blood pressure (DBP) was found at 0 h and significantly lower DBP was found at 12 h, 1 day, and 1 month after exposure. Significantly higher mean arterial pressure (MAP) was noted at 0 h and significantly lower MAP was noted at 1 day. CONCLUSIONS: Significant alterations in arterial blood pressure were observed in rats exposed to EMP exposure while heart rate was not altered. |
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Authors:
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Bao-Feng Li; Guo-Zhen Guo; Dong-Qing Ren; Jing-Li; Ruo-Bing Zhang |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of radiation biology Volume: 83 ISSN: 0955-3002 ISO Abbreviation: Int. J. Radiat. Biol. Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-05-09 Completed Date: 2007-07-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8809243 Medline TA: Int J Radiat Biol Country: England |
Other Details:
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Languages: eng Pagination: 421-9 Citation Subset: IM; S |
Affiliation:
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Department of Radiation Medicine, Fourth Military Medical University, Shannxi Province, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Flow Velocity / physiology, radiation effects* Blood Pressure / physiology, radiation effects* Dose-Response Relationship, Radiation Electromagnetic Fields* Heart Rate / physiology, radiation effects* Male Pulsatile Flow / physiology, radiation effects* Radiation Dosage Rats Rats, Sprague-Dawley Whole-Body Irradiation / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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